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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9a94a44d3cbebbf433f6f131a08587e0f916fa53cd35898cf3467963d20a98b' 
  AND token = 'BBDC6DdmHaTNVGTOomMZ7xBcdN6OfkBxbgWLUWEzaI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}