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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5670d60769e1f7e980a0f8181c4f687d9f3caa50237b73ba76752e100dafd3f3' 
  AND token = 'wo9TnMtG8Eyuh1Zds02+oyNO0h5Fe+4lzg4fzZqTVoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}