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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a746f1e5cfe6982c8560acf9f8a97434f6aeae673663e95fc470037f8c02f1' 
  AND token = 'Hcbem+Wo1d7qnaeZOpV+jnU60Z3ytAgNnsRWB3q/nj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}