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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5ec5ef40e7148262897f771c846004cc292d6a8c6c41b347ed405ead5c60755' 
  AND token = 'mQR+gVkTrOb5U/XZjjvYIux/1aHrYHZuDNd8EZ29lDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}