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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54bf9eeaade782c8d355423815359421e04a35086410628bc9e2229d93a2349a' 
  AND token = 'Kgjz9d8DYeTdPHZbRe95oHz0SEs1FQZOrIRvlkXVLqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}