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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ff9202fdb91cc215095d25cba2a48db9a0595eec5f757f276f570d107315cae' 
  AND token = 'I8ycrjqQ6pEF2xTiJM2qFMmtoHCssqCBi+lYGZeFxY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}