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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf21f83fe39dfc6a763bf5822a1fbee14d7371f8d8e6065d855c876825b5b766' 
  AND token = 'TodyESs6FjeCKkVN1ZsXTGo1NPNkl9I78waTgDHM+tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}