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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727cc9f0b6e36951fd9a7580c9e89cfebf5d0e22b838053e1057caf0e6461d28' 
  AND token = 'DDWVsADv1NGzEbJATxSqvV8NWTaq/R3xQ09dB8OOx/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}