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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc9f4ed0d61b0977728a448f75003a36c1c315f6f64eb76e561a415413460435' 
  AND token = 'e1eqTqEeWjTNWIz+xiI3NbMUvLL3olrkyfZmVJr8FT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}