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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f3bcac763fe7d6eb3b8b9e50825cfff8e9f53989ad86a70f9d5bf81d211387f' 
  AND token = '1PnmxX/t6ygpD0H+N6T4Gf4ZACjvCNGbnoHmY3aiecw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}