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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fa606f5a55eecfd334f8a884319f4f221c28bb7094109131f0e37de704b6bdb' 
  AND token = 'VWMRWASEL1qZi/9rf3z3pE9xmnaqc1S18AMo2zidbzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}