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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b949a2371baf00845f9fc59dc6703af1bb20f6794f3f01417fa19e802aadb9c' 
  AND token = 'hTKUX53H7MWbCc51DOm5goWteyBOvQmD2xt5W7E2oqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}