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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b2a3ef99fa26feea15ad9941a6caa79c86f5ca2e2de0c11c778f2e1ea27eab' 
  AND token = 'NxOVIAbV7J0bDF0P1V3uEE7hw7ol9VDMqBI4lB9I/FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}