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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce40ffde3e35b3cb2d7d6d749362de65317b955a60edf9967992c99aef2288c' 
  AND token = 'VLYr8uFFYYvos1XP66ARvLXH/uneACeGdJsIdf6kkWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}