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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1d6ac0645bb3705955046f835a081c8b0f6d72a06e6389acecdd9bacaecb98' 
  AND token = 'qfNhyoP6CcPkwDlnq649D/OB0t7ooUmr7WNeIxoMVYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}