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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57a99693b325154f05b7c2dd8ce729a37a58ceb4303bceb3f778e06fee04a79' 
  AND token = 'ZTDX8t7BVcd7rQ4lLqG3Ek/4pQR3H8KIpElSsgmSPIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}