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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4de442ad7685610ca33d8722a0855dd67afeac654209acd81f70b8870dca632' 
  AND token = 'bBWakTE+kII/xFjpnf5iIPMzAs5pRDuD1cTGE1diN0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}