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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd49ee9896851cdb08014a775d222091e333e4b60d6d587d629df75975f02113' 
  AND token = 'FXvTGBUmZpJ1BrSniy+k0WMM+qeqpG9qvh0+S7SijlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00085

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}