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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a0f95088e8bab84279bdfa0946cc3be8e2f4d33a52d1f56032e491ce7124ecf' 
  AND token = 'Iw0p1JBawN0rismXMuQ78Tc0yRVXlGNzV8n1PpOa+O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}