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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5dc127c069aef7edfbc5eac6b76588b8e377673ce6ddebe2a820bea731c283' 
  AND token = 'XikuLIKGVlSPE7d3/YhCMzgUuMDtfycFutRO/vjA0dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}