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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ee01f168848bee9ec1784294474cfe122ee11bea4ce8f35cb26c3ac6848d7c7' 
  AND token = '9/m6RAAwLHH0HrhPWtLdtRmtsipsq+kW5UFcyJ0iZto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}