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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa2481b6019b87f2f865abb8a1400267c6344b22bcd48e168e336130ad675f0' 
  AND token = 'D4JUQtZhsHHKI52QNLLhAPtG5ZNcKO3No1jYWQcASNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}