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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f8b6d0aad9be3e43edef5654e9b9991351d5555e2472ec57abf7aea8457d9a' 
  AND token = 'zj8mHP6Up1dDYQb7Yp3J/q5Rc9HwNr08Y38W5PadRGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}