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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf5f8c20383c7f65632342fa2d3646a50cadbd4def1b9cbc3deadadc8e53e29' 
  AND token = 'S4Z2+jWdA6d3EpK8YOABeZqzg3lpqi4RsAi2VCYwWsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}