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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff446a51f83d42dea2bed77b543abe1ecdef0dd0f95055c6b5445afcf1d92464' 
  AND token = 'n23fvBpRaM1mqowC1CQYVvn22w3oLiteOAUmHX3bH4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}