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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '361d4f57e4101de82f36408ff5766695803e3ed2046aadb080879747cf149540' 
  AND token = 'jn1Y2GoYiupLk6AiNvKxbkwQYM1UOZ13/Ykns1VUq3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}