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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4bbc3047a713ded4575fb0f8525fd28cae6a658127d4bef82e6c40f6cdcec61' 
  AND token = 'q0E3HVXmPyN4IKsgTlo6mJ6jBmnQIVaOIn+p+i65LYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}