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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e1126eb61b6f1ff0d27c22c560d39915fe19f0b44f8468f3599b53ec98b7e07' 
  AND token = '7nAyLrWKKB13zU4TRWOmM6N9HOzxN96HvSlDBi9XR10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}