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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75415fd98cc8dc49dca370aa4f63c477d9d9469b8858d3aa3e25f2f4e7127b87' 
  AND token = 'BQrtkoeltsIP+DCBc6AsSa+Ig2HB5n6wqwOiO4I72dY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}