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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cff2dcfac3ba085e0e7417b9d464e824e31c95c9e29c7ab693cd86bde3cade23' 
  AND token = 'LQn+GnDFO7E+aNyCTCqGEDKj63TJiBruvEq6Z8UxQ2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}