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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e27a42a2e2076b09b1d072385fb775b49bc688575c5b2c5e781db29940c00ee' 
  AND token = 'KRICvy4BTpky1sa84c99EAOm/LWqhxxbDj9vTMNT0Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}