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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99d6a5a2cb414a0c9f189f52ac3566a02e35159c51a49c5b7bd4827e87045a67' 
  AND token = 'SyVPxoElUFiboUdKg4xdW2f7rr0bmdWw79DzNWCywnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}