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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d86c53caad8a2d78fb170c8ba76e9f9fb502347a64ae7170183294a83ff9970' 
  AND token = 'lcLW7fW7TDuf+fVhNHWA4ucmv/kpaMHT3RI3kZMs6/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}