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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e0327d8a08451b1161ce8bf5969de0acf9c8a187beaa5f8be73d0fb570caf06' 
  AND token = 'VAKxpvYHzOtALFYNhRR3sSblFYnu0nY3zHBfs3ujL6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}