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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462595ab55678b953dfb6cd80095280ceeba5b6a78b8e3a833839b39f1eb7a7c' 
  AND token = 'tzrB37N3k3MukLLIuMmeZEOdG4QxYS/6F1D7htNY6TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}