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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270c6a783133330d7a2313d5f088af0f76a0504d1ce200ebf6ecb68035b1621d' 
  AND token = 'BnOtrLAmi1DrnIvbiAMzmty+xn0nEkpBoCBNZ+8+OJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}