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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7787f7475f1d888002dde09136176ed2b21bb6b7a039b7cc16527414d293d2e4' 
  AND token = 'XMG0vGyypc2229XB4GrbCLw8GxeYTEtmEUvw6hvvlGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}