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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d3d92f917d84fa9e09ad39a08677ab97d3804a9e7de894e8471cca29c6e2b0' 
  AND token = 'cuGr7xcESMVQwcJh4J2Tt3Uf7Aw/IcLyzVJKbeXksr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}