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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1898f76a9d1539225c09d51c49db962f80a76e6e75089b9e611a81df8689bac' 
  AND token = 'f2H1+txTKTqi9XPkEKhGxkYU0QrmaLcqyMvW6ypJuzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}