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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a9aa67eca0100d101265f26cae86f12ecfbb4c549406ce51be3cdf78778b7d9' 
  AND token = 'MSBrmYtov7+a52hBVMJKBQ5eS3c6Wz9IpgI00LFSwko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}