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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165f882a2fd4d686af715b09b13e6dacf64d9fa748f838eccd182527080c42ef' 
  AND token = '79Nvv8X1J1eGRh/CUKeqv6kzkzwWF25C/kvnzcvWfnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}