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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7787b0c969502df351130f295f06c8f47a4d8e67fc080625f4d136c2b80e6d10' 
  AND token = 'Zqbrf9MyM09+h6XuuiQLGx8pip8Po7kMsxGJRm7QXGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}