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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bbb00e4de7a80acd8dfcca489b6fa83e8fc8e36da1cbe1c51bbeeddd0b6e509' 
  AND token = 'W0xw+STBdjYYMSZ1JoB65BoDevEkAJDlCy8VK6EqvC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}