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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05aed9c7746e8382e4e2ba461e0524b0eebd7e40212de6ab4f9d593a84f0ea60' 
  AND token = 'zt4yPbia6BG/xTz4qL9UVLX8Xl/4mmPX7dMmW6r81IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}