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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a9f8d6604b0e5b4b6404f6292a5b5d521434219c4c779e1ba43bdcc9a7c55af' 
  AND token = 'MnOtDdBO+7PV0GB0fxJbY8eK8j7MuovLmwb96Js1fHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}