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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8042a48f590de204975efd74a300b282ba2518b318136b8036b3e0f74bf284e1' 
  AND token = 'uqqcp/DpexD1Dw4hWU45L0wfarIEnGiLEKBOb3W9t78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}