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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cda5388fbf4ccd2eab515d2a4b212f94f9e8940ff9b4fbe3d256f66487b504d' 
  AND token = 'hW1ArxyI68qAeYdnRKhCSqaRUTMU3TML0jaRWuK9jYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}