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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f050af585ec35d01d221ae46c24027d595aa1c4f5fcc1ec32f02f9c4c6c69bb' 
  AND token = 'r+Nb6LK+Ihium7CrSGHy4HpeCEPIsGMC3hg8khaov+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}