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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64491ac7085353f4b1fc229f8843aa209fdf617788bb783fe46decaa9ea39a61' 
  AND token = 'FCJMFBoNymiKfs41yl7a4UL179rTmieSNOoQ9enKInQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}