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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ae8d231b4f9e2b17ef02ba4b44b0d4175084ea3ddf044b0a560cbdbcba77b0' 
  AND token = 'kAwAc/c4f8BCXAOsYJeT+WjWXHIC+WT4yMq6TCVEZ38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}